Utilising PHE's antimicrobial resistance data in surveillance of NICE/PHE antimicrobial prescribing guidelines
PHE ePoster Library. Rawstrone C. Sep 12, 2019; 274400; 201
Mrs. Charlotte Rawstrone
Mrs. Charlotte Rawstrone
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Abstract
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Abstract Introduction
NICE/PHE antimicrobial prescribing guidelines (APGs) are evidence-based guidelines for managing common infections. APGs were developed as part of the UK five year antimicrobial resistance strategy 2013 to 2018 for tackling antimicrobial resistance, specifically in relation to antibiotic use. The annual English Surveillance Programme for Antimicrobial Utilisation and Resistance (ESPAUR) report focuses on antimicrobial resistance patterns to support the delivery of the UK's antimicrobial resistance strategy. NICE regularly checks guidelines are accurate through a guideline surveillance process.
Methods
The ESPAUR report is directly applicable to the antibiotic recommendations within the APGs and formed the basis of our guideline surveillance strategy. To maintain accuracy of the APGs, surveillance of the ESPAUR and the APGs was performed. A mapping exercise examined the antimicrobial prescribing recommendations in 10 APGs and compared them to the resistance rates for the drug/bug combinations in the 2018 ESPAUR report.
Results
Areas of increased resistance were highlighted, and the findings discussed with members of the guideline committee. The committee confirmed that despite some increased resistance, the antibiotics listed in the APGs were still the most relevant for that infection and concluded that the prescribing information was accurate.
Conclusion
Using the ESPAUR report in surveillance of NICE guidelines is a new process which has proved effective for the APGs. Annual surveillance will continue in this way and should play an important role in improving the consistency of antimicrobial recommendations across organisations. We will also consider how to keep this process efficient as the suite of APGs increases each year. External funding details
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