Tuberculosis among people with social risk factors
PHE ePoster Library. Wardle J. Apr 10, 2019; 257517; 15432
Jack Wardle
Jack Wardle
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Abstract
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Abstract Background:
While the overall number of people with TB in England has reduced by 38% since 2011, the number of cases with a social risk factor (which includes alcohol and drug misuse, homelessness and imprisonment) has remained approximately stable. This reflects the increased complexity of treating and controlling TB in these populations, particularly when patients have multiple social risk factors at the same time. This study aims to improve our understanding of the characteristics of TB cases with social risk factors and the effect that these have on treatment outcomes.
Methods:
:Adults (≥15 years old) notified to the Enhanced TB Surveillance system in England between 2010 and 2017 were analysed based on the presence of social risk factors. Univariable and multivariable logistic regression identified demographic and clinical characteristics associated with the presence of social risk factors, and the effect of social risk factors on TB treatment outcomes. The number of prevalent TB cases with social risk factors was also estimated.
Results:
:Between 2010 and 2017, 10.1% (4,566/40,513) of TB cases had a social risk factor, with an increase in the proportion over time (2010: 9.9% (584/5,899) vs 2017: 12.6% (549/4,341)). Social risk factors were common in people born in the UK (18.8%, 2,010/10,715), males (14.7%, 3,793/25,893), the Black-Caribbean ethnic group (33.8%, 190/562) and people with pulmonary TB (15.1%, 3,516/23,259)..
Results:
from future univariable and multivariable analyses and prevalence estimates will be reported at the conference.Relevance:This study improves our understanding of the characteristics of a population group where it has been difficult to reduce levels of TB in recent years. The evidence generated will inform a number of ongoing activities that seek to improve access to services and provide integrated clinical and social care to these under-served populations.
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