The effectiveness of interventions to reduce symptomatic urinary tract infections and E.coli bacteraemia in hospital and care home residents, a systematic review.
PHE ePoster Library. Jones L. Sep 12, 2017; 186678; 193
Ms. Leah Jones
Ms. Leah Jones
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Abstract BackgroundSurveillance has indicated an alarming rise in rates of Escherichia coli (E. coli) bacteraemia with highest rates in England observed amongst the elderly. On-going mandatory surveillance continues to identify previous Urinary Tract Infections (UTI) as a key risk factor.The objective of this systematic review is to examine the effectiveness of interventions aimed at reducing rates of E.coli bacteraemia and/or reducing UTI.MethodsA search strategy using the PICO framework will be used to identify studies meeting the inclusion criteria published since 1990. Electronic databases, grey literature and reference lists will be searched for studies and managed in EndNoteX7.During primary screening, titles and/or abstracts will be scanned for relevance. All studies selected will be read in full against the inclusion and exclusion criteria to confirm suitability. ResultsA meta-analysis will be undertaken if studies are considered sufficiently similar regarding patient characteristics, interventions and outcomes.A narrative synthesis technique will likely be used to combine the evidence from the included studies for this review. Clinical heterogeneity will be explored by examining factors that may be influential such as care setting, patient characteristics and intervention characteristics.ConclusionInterventions that reduce prevalence of UTIs and E.coli infections in the elderly will have positive implications on mortality and morbidity, resulting in better patient outcomes and therefore fewer antibiotics being prescribed. Overall, successful interventions can improve patient outcomes, satisfaction of care from families, and a reduction in national E.coli rates which will have further implications for both primary and secondary quality of care.
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