Congenital Zika Syndrome: establishing obstetric and paediatric surveillance in the UK and ROI
PHE ePoster Library. Oeser C. 09/13/16; 137907; 234
Dr. Clarissa Oeser
Dr. Clarissa Oeser
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Abstract The Zika virus outbreak, mostly focussed in South and Central America and the Caribbean, has been declared a Public Health Emergency of International Concern byWHO in February 2016. Based on a growing body of research, there is scientific consensus that Zika virus is a cause of microcephaly and other congenital abnormalities. Cases of maternal fetal transmission of Zika virus have been confirmed and a number of congenital abnormalities potentially associated with maternal Zika virus infection have been described. The risks and impact on UK travellers to affected countries is not clear. Surveillance for congenital abnormalities potentially associated with Zika virus infection has been rapidly established in the UK and Republic of Ireland. The UK Obstetric Surveillance System (UKOSS) started UK surveillance of pregnancy outcomes in mothers who have travelled to a country with active Zika transmission on 1st March 2016. Detailed reports will be collected on all adverse outcomes including miscarriages, still births and terminations. The British Paediatric Surveillance Unit (BPSU) records all infants ≤ months of age with microcephaly or neurological abnormalities born in the UK and ROI to mothers who have travelled to affected countries. Surveillance commenced 1st April. The studies aim to establish the number of cases and the risk of congenital abnormalities associated with travel to a country with active Zika virus transmission. In addition, findings may help to describe the typical features and natural history of this condition, including presentations in relation to time of infection during different stages of pregnancy.
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